Happy Wednesday Zingers! It’s always nice when a pilot can cut a couple of minutes off their expected flight time. But, like most good things, speeding in the air is best done in moderation.

Recently a few international flights got caught in 260 MPH winds that propelled the planes to more than 800 MPH, breaking the speed of sound. Some videos of the flights are going around - I think I’ll be just fine with going a normal speed on my next flight and being a few minutes late, thank you very much.

Before we dive in, today’s partner is taking a different approach to treating cancer, like colon cancer. Click here to read more.

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MARKET SNAPSHOT

Yesterday: Stocks moved lower yesterday, with NVIDIA dropping more than 4%, dragging the tech sector lower. Walmart was one of the best performers of the day, closing up more than 3% on a strong earnings report.

On Our Radar: Some Fed communication throughout the day, but all eyes will be on NVIDIA’s earnings report after the close. Will the leading chip company deliver, or were our expectations just a little too high?

TOP STORY

Nvidia's Earnings to Set Tone for AI Investment Rush

The start of 2024 sparked a debate among investors regarding the monetization of the AI Revolution, marking a significant shift in the tech landscape akin to the emergence of the Internet in 1995, Wedbush analyst Daniel Ives said.

• The key focus was on enterprise spending trends, seen as crucial to validate lofty valuations and pave the growth path for the year and beyond, as per the analyst.

Microsoft’s Copilot program exceeded expectations, indicating robust demand for AI deployments among its clientele.

Attention now turns to Nvidia regarded as the pioneer of AI, as it prepares to announce its earnings and provide guidance, Ives said. 

• The tech community awaits Nvidia’s insights with bated breath, anticipating another impressive performance and bullish outlook.

What to Watch: Investors are particularly interested in the pace of data center AI spending, as Nvidia remains the primary choice for GPUs powering generative AI applications. 

Go Deeper: We have the full story, check out more here.

PRESENTED BY ELICIO THERAPEUTICS

How Elicio Therapeutics Is Taking A Different Approach To Treating Cancers Like Colon Cancer, Expected To Be The Leading Killer Cancer By 2030

Elicio Therapeutics is at the forefront of cancer care with its AMP platform, transforming the landscape with cutting-edge immunotherapies. These innovations are designed not just to treat, but to strategically target and dismantle the very mutations that propel pancreatic and colon cancers. 

The company's leading candidate, ELI-002, embodies this approach, aiming to deliver accessible, non-customized vaccines that promise a new dawn for cancer treatment efficacy and availability.

Though further studies are needed to confirm its efficacy, the shot could improve survival for colon cancer, expected to be the number one cause of cancer deaths for people between 20-49 years of age by 2030, and pancreatic cancer, which has just a 12% survival rate after five years. 

There’s more, click here to keep reading.

FIVE ZINGERS

Just Keep Spending: U.S. government debt now exceeds 120% of GDP… here’s why one economist is worried.

That’ll Do: Bill Ackman and Pershing Square outperformed nearly every other hedge fund last quarter. Here’s what he was investing in.

The House Always Wins: But maybe not this quarter. Caesars reported earnings after the close yesterday, and they were a little light.

Apple Shakeup: The engineer in charge of the audio for AirPods and other Apple products is stepping down. Here’s what you need to know.

Forgiven: The Biden administration has announced the forgiveness of $1.2 billion in student loans, relieving more than 150,000 borrowers.

ONE FOR THE ROAD

Amazon Stock Pops On Dow Jones Inclusion

Briefly: Amazon shares traded higher in Tuesday’s after-hours session after the company was selected to replace Walgreens within the Dow Jones Industrial Average (DJIA).

What Happened: In a new press release issued Tuesday, S&P Dow Jones Indices announced that Amazon will replace Walgreens in the DJIA, effective before the market opens on Feb. 26. Amazon shares rose 1.20% after-hours following the announcement.

A Change-Up: Walmart’s 3:1 split announcement prompted this change. Walmart’s index weighting will be reduced, but the company will remain in the DJIA. Adding in Amazon will increase consumer retail exposure in the Dow.

Anything Else? S&P Dow Jones Indices also announced that Uber will replace JetBlue Airways in the Dow Jones Transportation Average to help the index gain exposure to the ride-sharing industry.

What Next: Read the full breakdown here.  

PRESENTED BY ELICIO THERAPEUTICS

Elicio Therapeutics (NASDAQ: ELTX) Reports Promising Progress In Cancer Vaccine Clinical Trials, Placing An Emphasis On The Lymphatic System

An estimated 609,820 people will die of cancer in the United States this year. Promising results from a 12-year-old clinical-stage biotechnology company have experts optimistic about the future of treating this deadly disease. 

With its proprietary Amphiphile or “AMP” platform, Elicio Therapeutics Inc. has developed multiple cancer vaccine candidates that concentrate an array of different immunogens in the lymph nodes. 

ELI-002 is Elicio’s lead clinical program for Kirsten rat sarcoma (KRAS) driven cancers caused by a mutation of the KRAS gene.

Click here to learn more and see what’s in store for Elicio Therapeutics in 2024.